Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 7/20 | 0.85 |
| ▸ | APP | P05067 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30295042 | 1.00 | PTGER4 (0.85) | PTGER4APPMEN1KMT2ASRC | |
| SCHEMBL12479908 | 1.00 | PTGER4 (0.85) | PTGER4APPMEN1KMT2ASRC | |
| SCHEMBL13635119 | 0.93 | PTGER4 (0.73) | PTGER4APPMEN1KMT2AKDM4E | |
| SCHEMBL15774498 | 0.92 | PTGER4 (1.00) | PTGER4APPMEN1KMT2ASRC | |
| SCHEMBL15901783 | 0.86 | PTGER4 (0.64) | PTGER4APPMEN1KMT2AKDM4E | |
| SCHEMBL15774938 | 0.86 | PTGER4 (0.88) | PTGER4APPSRCKDM4EPKM | |
| SCHEMBL28288523 | 0.85 | PTGER4 (0.63) | PTGER4APPCNR2 | |
| SCHEMBL26262783 | 0.85 | PTGER4 (0.86) | PTGER4APPSRCALDH1A1CNR2 | |
| SCHEMBL2143204 | 0.84 | MEN1 (0.62) | PTGER4APPMEN1KMT2AKDM4E | |
| SCHEMBL13387568 | 0.84 | MEN1 (0.70) | PTGER4APPMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795694-B2 | Imaging beta-amyloid peptides aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-10-24 | — | — | US | disclosed |
| US-9795694-B2 | Imaging beta-amyloid peptides aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2017-10-24 | — | — | US | disclosed |
| CN-102743769-B | Imaging of beta-amyloid peptide and inhibition of beta-amyloid peptide aggregation | 香港浸会大学 | 2016-11-02 | — | — | CN | disclosed |
| US-20160243264-A1 | Imaging Beta-Amyloid Peptides Aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2016-08-25 | — | — | US | disclosed |
| US-20160243264-A1 | Imaging Beta-Amyloid Peptides Aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2016-08-25 | — | — | US | disclosed |
| US-9403794-B2 | Imaging beta-amyloid peptides and inhibition of beta-amyloid peptide aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2016-08-02 | — | — | US | disclosed |
| US-9255933-B2 | Imaging beta-amyloid peptides and inhibition of beta-amyloid peptide aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2016-02-09 | — | — | US | disclosed |
| US-9156814-B2 | Imaging beta-amyloid peptides and inhibition of beta-amyloid peptide aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2015-10-13 | — | — | US | disclosed |
| US-20140213614-A1 | Imaging Beta-Amyloid Peptides and Inhibition of Beta-Amyloid Peptide Aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2014-07-31 | — | — | US | disclosed |
| US-20140212360-A1 | Imaging Beta-Amyloid Peptides and Inhibition of Beta-Amyloid Peptide Aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2014-07-31 | — | — | US | disclosed |
| US-20120269738-A1 | Imaging Beta-Amyloid Peptides and Inhibition of Beta-Amyloid Peptide Aggregation | HONG KONG BAPTIST UNIVERSITY (HK) | 2012-10-25 | — | — | US | disclosed |
| CN-102743769-A | Imaging of Beta-amyloid peptide and inhibition of Beta-amyloid Peptide aggregation | UNIV HONG KONG BAPTIST | 2012-10-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120269738-A1 | Imaging Beta-Amyloid Peptides and Inhibition of Beta-Amyloid Peptide Aggregation | APP, IAPP, BACE1 | PTGER4 4506/4885APP 1/4885MEN1 1083/4885 |
| US-20140213614-A1 | Imaging Beta-Amyloid Peptides and Inhibition of Beta-Amyloid Peptide Aggregation | APP, IAPP, BACE1 | PTGER4 4252/4885APP 1/4885MEN1 1083/4885 |
| US-20160243264-A1 | Imaging Beta-Amyloid Peptides Aggregation | APP, IAPP, APBA1 | PTGER4 4526/4885APP 1/4885MEN1 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.