SCHEMBL133876

SCHEMBL133876

COc1ccc(C=O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 1.00
TRIM24 O15164 1/20 1.00
TRIM33 Q9UPN9 1/20 1.00
ERN1 O75460 4/20 0.72
ALDH1A1 P00352 4/20 0.63
CYP1A2 P05177 2/20 0.59
CYP1A1 P04798 1/20 0.59
CYP1B1 Q16678 1/20 0.59
AR P10275 1/20 0.54
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
MAPK1 P28482 2/20 0.52
CYP3A4 P08684 1/20 0.52
HPGD P15428 1/20 0.52
GSK3B P49841 1/20 0.51
MAPT P10636 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CYP2C19 P33261 1/20 0.49
KDM4E B2RXH2 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28337239 0.98 TYR (0.96) TYRTRIM24TRIM33ERN1ALDH1A1
SCHEMBL28150290 0.98 TYR (0.96) TYRTRIM24TRIM33ERN1ALDH1A1
SCHEMBL11420339 0.98 TYR (0.96) TYRTRIM24TRIM33ERN1ALDH1A1
Hydrogen Sulfide SCHEMBL28156220 0.98 TYR (0.96) TYRTRIM24TRIM33ERN1ALDH1A1
SCHEMBL4456426 0.98 TYR (0.96) TYRTRIM24TRIM33ERN1ALDH1A1
Formamide SCHEMBL28559416 0.94 TYR (0.89) TYRTRIM24TRIM33ERN1ALDH1A1
Formaldehyde SCHEMBL28559418 0.94 TYR (0.89) TYRTRIM24TRIM33ERN1ALDH1A1
Alcohol SCHEMBL28458502 0.93 TYR (0.86) TYRTRIM24TRIM33ERN1ALDH1A1
Acetonitrile SCHEMBL29178537 0.91 TYR (0.83) TYRTRIM24TRIM33ERN1ALDH1A1
Bicarbonate SCHEMBL28156948 0.91 TYR (0.83) TYRTRIM24TRIM33ERN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2881 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567439-B Dual-channel near-infrared ratio fluorescent probe for detecting tyrosinase and preparation method and application thereof 安徽大学 2026-05-15 CN claimed
CN-122004347-A Method for producing high-digestibility feed based on penicillium sclerotium fermentation zingiberaceae plants and application thereof 华南农业大学 2026-05-12 CN claimed
CN-118047770-B Mitochondria-targeted near infrared fluorescent probe, preparation method thereof and application thereof in carboxylesterase detection 安徽大学 2026-05-12 CN claimed
US-20260101914-A1 VANILLA COMPOSITION FIRMENICH & CIE (CH) 2026-04-16 US claimed
EP-4168255-B1 ELASTOMERIC COMPOSITION COMPRISING A PHENOLIC COMPOUND AND A COMPOUND FROM THE MONOSACCHARIDE FAMILY MICHELIN & CIE (FR) 2026-03-04 EP claimed
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US claimed
EP-4659830-A2 EFFICIENT DEPOLYMERIZATION METHOD OF POLYMER COMPRISING ESTER FUNCTIONAL GROUP, AND PURIFICATION METHOD THEREOF Korea Research Institute of Chemical Technology (KR) 2025-12-10 EP claimed
US-20250280857-A1 DEGRADATION-RESISTANT ALDEHYDE-CONTAINING COMPOSITIONS ZOOMESSENCE INC (US) 2025-09-11 US claimed
US-20250228841-A1 COMPOSITIONS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES APTORUM THERAPEUTICS LTD (HK) 2025-07-17 US claimed
CN-120192271-A Schiff base and preparation method thereof, schiff base optical switch and preparation method thereof and optical element 安徽省东超科技有限公司 2025-06-24 CN claimed
US-5931995-A Ink compositions XEROX CORPORATION (US) 1999-08-03 US claimed
EP-0845026-A1 MULTICOMPONENT SYSTEM FOR USE WITH DETERGENT SUBSTANCES CALL, Hans-Peter Dr. (DE) 1998-06-03 EP claimed
WO-1997048786-A1 MULTICOMPONENT SYSTEM FOR USE WITH DETERGENT SUBSTANCES CALL HANS PETER (DE) 1997-12-24 WO claimed
US-5663022-A Recording sheets XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0674232-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 EP claimed
EP-0267944-A4 BINDING ASSAYS INVOLVING FORMATION AND DETECTION OF LIGHT-SCATTERING CRYSTALS 1990-09-12 EP claimed
EP-0267944-A1 BINDING ASSAYS INVOLVING FORMATION AND DETECTION OF LIGHT-SCATTERING CRYSTALS ARTHUR D. LITTLE, INC. (US) 1988-05-25 EP claimed
US-4727024-A Binding assays involving formation and detection of light scattering crystals ARTHUR D. LITTLE, INC. 1988-02-23 US claimed
WO-1987007027-A1 BINDING ASSAYS INVOLVING FORMATION AND DETECTION OF LIGHT-SCATTERING CRYSTALS ARTHUR D. LITTLE, INC. (US) 1987-11-19 WO claimed
US-4473713-A Hydrolysis of aryl-aliphatic ethers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-09-25 US claimed