⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5689030 | 0.83 | — | — | |
| SCHEMBL6416273 | 0.69 | — | — | |
| SCHEMBL4195110 | 0.67 | — | — | |
| SCHEMBL7221897 | 0.66 | — | — | |
| SCHEMBL160163 | 0.65 | — | — | |
| SCHEMBL3913409 | 0.65 | — | — | |
| SCHEMBL868176 | 0.65 | — | — | |
| SCHEMBL1006026 | 0.65 | — | — | |
| SCHEMBL1340001 | 0.65 | — | — | |
| SCHEMBL11133453 | 0.62 | BACE1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112724168-B | Chiral pyridine derived N, B ligand, preparation method and application in iridium-catalyzed asymmetric boronation reaction | 西安交通大学 | 2021-12-28 | — | — | CN | claimed |
| CN-112724168-A | Chiral pyridine derived N, B ligand, preparation method and application in iridium-catalyzed asymmetric boronation reaction | 西安交通大学 | 2021-04-30 | — | — | CN | claimed |
| EP-1673321-B9 | METHOD OF PREPARING FULVENE COMPOUNDS AND METHOD OF PREPARING ANSA-METALLOCENE COMPOUNDS USING THE COMPOUNDS | LG CHEMICAL LTD (KR) | 2015-04-22 | — | — | EP | claimed |
| EP-1673321-B1 | METHOD OF PREPARING FULVENE COMPOUNDS AND METHOD OF PREPARING ANSA-METALLOCENE COMPOUNDS USING THE COMPOUNDS | LG CHEMICAL LTD (KR) | 2014-09-17 | — | — | EP | claimed |
| US-7166731-B2 | Method of preparing fulvene compounds and method of preparing ansa-metallocene compounds using the compounds | LG CHEM. LTD. (KR) | 2007-01-23 | — | — | US | claimed |
| EP-1673321-A1 | METHOD OF PREPARING FULVENE COMPOUNDS AND METHOD OF PREPARING ANSA-METALLOCENE COMPOUNDS USING THE COMPOUNDS | LG Chem, Ltd. (KR) | 2006-06-28 | — | — | EP | claimed |
| WO-2005035470-A1 | METHOD OF PREPARING FULVENE COMPOUNDS AND METHOD OF PREPARING ANSA-METALLOCENE COMPOUNDS USING THE COMPOUNDS | LG CHEM. LTD. (KR) | 2005-04-21 | — | — | WO | claimed |
| US-20050080296-A1 | Method of preparing fulvene compounds and method of preparing ansa-metallocene compounds using the compounds | LG CHEM. LTD. (KR) | 2005-04-14 | — | — | US | claimed |
| CN-121673156-A | Preparation method of 2-bromo-2-cyclopentenone | 南通华祥医药科技有限公司 | 2026-03-17 | — | — | CN | disclosed |
| CN-121673156-A | Preparation method of 2-bromo-2-cyclopentenone | 南通华祥医药科技有限公司 | 2026-03-17 | — | — | CN | disclosed |
| WO-2025067464-A1 | HETEROARYL COMPOUND, INTERMEDIATE THEREOF, AND PREPARATION METHOD AND USE THEREFOR | 杭州圣域生物医药科技有限公司 | 2025-04-03 | — | — | WO | disclosed |
| CN-119708015-A | Heteroaryl compounds, intermediates, preparation and use thereof | 杭州圣域生物医药科技有限公司 | 2025-03-28 | — | — | CN | disclosed |
| EP-4380565-A1 | HPK1 ANTAGONISTS AND USES THEREOF | Nimbus Saturn, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| WO-2024044486-A1 | JAK2 INHIBITOR COMPOUNDS | AJAX THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| EP-0863134-A1 | 2-(3,5-difluorophenyl)-3-(4-(methyl-sulfonyl)phenyl)-2-cyclopenten-1-one useful as an inhibitor of cyclooxygenase-2 | MERCK FROSST CANADA INC. (CA) | 1998-09-09 | — | — | EP | disclosed |
| US-5698584-A | NON-STEROIDAL ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA, INC. (CA) | 1997-12-16 | — | — | US | disclosed |
| WO-1997040012-A1 | PYRIDINYL-2-CYCLOPENTEN-1-ONES AS SELECTIVE CYCLOOXYGENASE-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1997-10-30 | — | — | WO | disclosed |
| WO-1997016435-A1 | 3,4-DIARYL-2-HYDROXY-2,5-DIHYDROFURANS AS PRODRUGS TO COX-2 INHIBITORS | MERCK FROSST CANADA INC. (CA) | 1997-05-09 | — | — | WO | disclosed |
| US-4061672-A | Derivatives of 9-hydroxy-13-trans-prostenoic acid | AMERICAN CYANAMID COMPANY (US) | 1977-12-06 | — | — | US | disclosed |
| US-3932487-A | HYPOTENSIVE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-13 | — | — | US | disclosed |