SCHEMBL13388754

SCHEMBL13388754

CC1(C)c2ccccc2-c2ccc(-c3ccc4c(c3)C(C)(C)c3cc(-c5ccccn5)ccc3-4)cc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 10/20 0.59
KDM4E B2RXH2 2/20 0.39
CYP1A2 P05177 2/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
CCR1 P32246 1/20 0.39
CCR5 P51681 1/20 0.39
CCR8 P51685 1/20 0.39
METAP1 P53582 1/20 0.39
BLM P54132 1/20 0.39
HIF1A Q16665 1/20 0.39
DOHH Q9BU89 1/20 0.39
P4HTM Q9NXG6 1/20 0.39
NPC1 O15118 1/20 0.39
CTSD P07339 1/20 0.39
BACE1 P56817 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP19A1 P11511 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3392580 0.98 PDK2 (0.61) PDK2KDM4ECYP1A2LMNAPOLB
SCHEMBL30772301 0.98 PDK2 (0.61) PDK2KDM4ECYP1A2LMNAPOLB
SCHEMBL14508228 0.97 PDK2 (0.57) PDK2KDM4ECYP1A2LMNAPOLB
SCHEMBL14508133 0.96 PDK2 (0.56) PDK2CTSDBACE1CYP2A6
SCHEMBL14508229 0.96 PDK2 (0.56) PDK2CTSDBACE1CYP2A6
SCHEMBL14508209 0.96 PDK2 (0.56) PDK2CTSDBACE1CYP2A6
SCHEMBL14508140 0.96 PDK2 (0.56) PDK2CTSDBACE1CYP2A6
SCHEMBL14508152 0.94 PDK2 (0.54) PDK2KDM4ECYP1A2LMNAPOLB
SCHEMBL15603678 0.94 PDK2 (0.54) PDK2KDM4ECYP1A2LMNAPOLB
SCHEMBL14508194 0.94 PDK2 (0.54) PDK2KDM4ECYP1A2LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7704609-B2 Compound and organic electroluminescense device using the same CANON KABUSHIKI KAISHA (JP) 2010-04-27 US disclosed
US-7704609-B2 Compound and organic electroluminescense device using the same CANON KABUSHIKI KAISHA (JP) 2010-04-27 US disclosed