Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28140185 | 0.76 | HSD17B10 (0.68) | HSD17B10POLBHTTTDP1KDM4E | |
| SCHEMBL28139608 | 0.75 | HSD17B10 (0.56) | HSD17B10POLBHTTTDP1KDM4E | |
| SCHEMBL4597893 | 0.74 | HSD17B10 (0.74) | HSD17B10POLBHTTTDP1HDAC2 | |
| SCHEMBL12936131 | 0.74 | HSD17B10 (0.58) | HSD17B10POLBHTTTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL21641210 | 0.73 | HSD17B10 (0.57) | HSD17B10POLBHTTTDP1KDM4E | |
| Hydrochloric Acid SCHEMBL12804218 | 0.73 | HSD17B10 (0.56) | HSD17B10POLBHTTTDP1KDM4E | |
| SCHEMBL10285704 | 0.72 | KDM4E (0.57) | HSD17B10POLBKDM4EALDH1A1 | |
| SCHEMBL19132875 | 0.72 | HSD17B10 (0.55) | HSD17B10POLBHTTTDP1KDM4E | |
| SCHEMBL13060936 | 0.70 | CYP2C19 (0.56) | HSD17B10POLBKDM4EALDH1A1 | |
| SCHEMBL4597891 | 0.69 | HSD17B10 (0.78) | HSD17B10POLBHTTTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010034796-A1 | 1H-BENZ IMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |