Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 7/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.41 |
| ▸ | PDE1A | P54750 | 2/20 | 0.41 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13394072 | 0.91 | ADORA2A (0.41) | PIK3CDADORA2AADORA1 | |
| SCHEMBL12112237 | 0.91 | PDE4A (0.42) | PIK3CDPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15214783 | 0.90 | PDE4A (0.41) | PIK3CDPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12112249 | 0.89 | SLC29A1 (0.43) | PIK3CDADORA2AADORA1YTHDC1 | |
| SCHEMBL12112243 | 0.83 | PIK3CD (0.40) | PIK3CDPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15214785 | 0.82 | PIK3CD (0.37) | PIK3CDPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12112236 | 0.81 | PIK3CD (0.47) | PIK3CDADORA2AADORA1 | |
| SCHEMBL13394115 | 0.80 | PIK3CD (0.41) | PIK3CDADORA2AADORA1 | |
| SCHEMBL16123777 | 0.80 | PIK3CD (0.41) | PIK3CDADORA2AADORA1 | |
| SCHEMBL12112232 | 0.79 | PIK3CD (0.39) | PIK3CDADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039187-A2 | FUSED DIIMIDAZODIAZEPINE COMPOUNDS AND METHODS OF USE AND MANUFACTURE THEREOF | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (US) | 2010-04-08 | — | — | WO | disclosed |