Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.55 |
| ▸ | MAOB | P27338 | 8/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318182 | 0.86 | MAOB (0.71) | APPMAOBDHODHMAOAACHE | |
| SCHEMBL3318179 | 0.86 | MAOB (0.71) | APPMAOBDHODHMAOAACHE | |
| SCHEMBL3321946 | 0.77 | MAOB (0.56) | APPMAOBMAOABCHEACHE | |
| SCHEMBL3321947 | 0.77 | MAOB (0.56) | APPMAOBMAOABCHEACHE | |
| SCHEMBL4735523 | 0.76 | MAOB (0.74) | APPMAOBALDH1A1MAPTHPGD | |
| SCHEMBL5548181 | 0.70 | MAOB (0.47) | APPMAOBMAPTMAOA | |
| SCHEMBL8466218 | 0.70 | MAOB (0.73) | APPMAOBDHODHALDH1A1MAPT | |
| SCHEMBL8466221 | 0.70 | MAOB (0.73) | APPMAOBDHODHALDH1A1MAPT | |
| SCHEMBL4732781 | 0.70 | MAOB (0.76) | APPMAOBALDH1A1MAPTHPGD | |
| SCHEMBL29531186 | 0.70 | MAOB (0.76) | APPMAOBALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | 4SC AG (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | BAX, BCL2, BAD | APP 4704/4885MAOB 3517/4885DHODH 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.