Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.74 |
| ▸ | CA1 | P00915 | 10/20 | 0.74 |
| ▸ | CA2 | P00918 | 10/20 | 0.74 |
| ▸ | CA4 | P22748 | 10/20 | 0.74 |
| ▸ | CA9 | Q16790 | 10/20 | 0.74 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.71 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5049403 | 1.00 | CA12 (0.74) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5049398 | 0.99 | CA12 (0.73) | CA12CA1CA2CA4CA9 | |
| SCHEMBL4948341 | 0.96 | CA12 (0.80) | CA12CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL6059996 | 0.95 | CA12 (0.78) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5049400 | 0.92 | PTGER2 (0.72) | CA12CA1CA2CA4CA9 | |
| SCHEMBL4943989 | 0.91 | CA12 (0.80) | CA12CA1CA2CA4CA9 | |
| Hydrochloric Acid SCHEMBL5046767 | 0.90 | CA12 (0.76) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5047904 | 0.89 | CA12 (0.71) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5043167 | 0.89 | PTGER2 (0.64) | CA12CA1CA2CA4CA9 | |
| SCHEMBL5726193 | 0.89 | CA12 (0.66) | CA12CA1CA2CA4CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105905-A1 | EP2 Agonists | PFIZER INC. | 2010-04-29 | — | — | US | disclosed |
| US-20100105905-A1 | EP2 Agonists | PFIZER INC. | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105905-A1 | EP2 Agonists | PTGER2, PTGER1, PTGIR | CA12 4207/4885CA1 4803/4885CA2 855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.