Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.65 |
| ▸ | DPP7 | Q9UHL4 | 16/20 | 0.65 |
| ▸ | FAP | Q12884 | 14/20 | 0.65 |
| ▸ | DPP8 | Q6V1X1 | 12/20 | 0.65 |
| ▸ | DPP9 | Q86TI2 | 11/20 | 0.65 |
| ▸ | PREP | P48147 | 6/20 | 0.47 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658501 | 1.00 | DPP4 (0.65) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL15386487 | 1.00 | DPP4 (0.65) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL13285822 | 0.97 | DPP4 (0.64) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL15028072 | 0.91 | DPP4 (0.58) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL13263360 | 0.89 | DPP4 (0.58) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL13382231 | 0.89 | DPP4 (0.58) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL12658521 | 0.86 | DPP4 (0.70) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL15386482 | 0.86 | DPP4 (0.70) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL13263475 | 0.85 | DPP4 (0.59) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL15386479 | 0.84 | DPP4 (0.67) | DPP4DPP7FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691967-B2 | Smart pro-drugs of serine protease inhibitors | TRUSTEES OF TUFTS COLLEGE (US) | 2010-04-06 | — | — | US | disclosed |