Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 12/20 | 0.54 |
| ▸ | HTR2C | P28335 | 12/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13398559 | 0.95 | HTR2A (0.60) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL13399068 | 0.89 | HTR2A (0.53) | HTR2AHTR2CSLC6A4HTR1A | |
| SCHEMBL13399032 | 0.86 | HTR2A (0.57) | HTR2AHTR2CSLC6A4HTR1A | |
| SCHEMBL13398818 | 0.86 | HTR2A (0.47) | HTR2AHTR2CSLC6A4HTR1A | |
| SCHEMBL13399524 | 0.84 | HTR2A (0.59) | HTR2AHTR2CSLC6A4HTR1A | |
| SCHEMBL13398761 | 0.83 | HTR2A (0.57) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL13398809 | 0.80 | SLC6A4 (0.47) | HTR2AHTR2CSLC6A4 | |
| SCHEMBL13399233 | 0.79 | HTR2A (0.59) | HTR2AHTR2CSLC6A4HTR1A | |
| SCHEMBL13398688 | 0.78 | SLC6A4 (0.56) | HTR2AHTR2CSLC6A4HTR1A | |
| SCHEMBL13398752 | 0.76 | HTR2A (0.52) | HTR2AHTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038948-A2 | ARYLPIPERAZINE-CONTAINING PYRROLE 3-CARBOXAMIDE DERIVATIVES FOR TREATING DEPRESSIVE DISORDERS | GREEN CROSS CORPORATION (KR) | 2010-04-08 | — | — | WO | disclosed |