Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.71 |
| ▸ | TACR2 | P21452 | 1/20 | 0.69 |
| ▸ | HRH2 | P25021 | 1/20 | 0.69 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.69 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.69 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3275000 | 0.85 | GNRHR (0.69) | GNRHRTACR2HRH2OPRM1OPRD1 | |
| SCHEMBL13403303 | 0.85 | GNRHR (0.64) | GNRHRTACR2HRH2OPRM1OPRD1 | |
| SCHEMBL3275214 | 0.83 | GNRHR (1.00) | GNRHRTACR2HRH2OPRM1OPRD1 | |
| SCHEMBL3279181 | 0.83 | GNRHR (0.75) | GNRHRTACR2HRH2OPRM1OPRD1 | |
| SCHEMBL13403224 | 0.82 | GNRHR (0.65) | GNRHRTACR2HRH2OPRM1OPRD1 | |
| SCHEMBL13403167 | 0.82 | GNRHR (0.70) | GNRHR | |
| SCHEMBL3275225 | 0.81 | GNRHR (1.00) | GNRHRTACR2HRH2OPRM1OPRD1 | |
| SCHEMBL30416471 | 0.81 | GNRHR (1.00) | GNRHRTACR2HRH2OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL5320375 | 0.81 | GNRHR (0.98) | GNRHRTACR2HRH2OPRM1OPRD1 | |
| SCHEMBL3274992 | 0.81 | GNRHR (0.74) | GNRHRTACR2HRH2OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696210-B2 | Gonadotropin releasing hormone receptor antagonists | WYETH (US) | 2010-04-13 | — | — | US | disclosed |