Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 18/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405659 | 0.89 | CSF1R (0.74) | CSF1RPOLBATM | |
| SCHEMBL13439323 | 0.85 | CSF1R (1.00) | CSF1R | |
| SCHEMBL13405655 | 0.80 | CSF1R (0.75) | CSF1RPOLBATM | |
| SCHEMBL13147770 | 0.78 | CSF1R (0.71) | CSF1RPOLBATM | |
| SCHEMBL12381966 | 0.76 | CSF1R (0.44) | CSF1RPOLBATM | |
| SCHEMBL12381938 | 0.75 | CSF1R (0.42) | CSF1RPOLBATM | |
| SCHEMBL13405658 | 0.74 | CSF1R (0.76) | CSF1RNTRK1KITAXLFLT3 | |
| SCHEMBL13439370 | 0.73 | CSF1R (1.00) | CSF1R | |
| SCHEMBL13405642 | 0.71 | CSF1R (0.81) | CSF1R | |
| SCHEMBL31157978 | 0.71 | CSF1R (0.81) | CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705042-B2 | Class of arylamide compounds useful as inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA NV (BE) | 2010-04-27 | — | — | US | disclosed |