Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 18/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 16/20 | 0.52 |
| ▸ | CCR7 | P32248 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13407514 | 0.89 | CXCR2 (0.44) | CXCR2CXCR1CCR7 | |
| SCHEMBL13439977 | 0.88 | CXCR2 (0.61) | CXCR2CXCR1CCR7 | |
| SCHEMBL13407246 | 0.88 | CXCR2 (0.61) | CXCR2CXCR1CCR7 | |
| SCHEMBL13407248 | 0.85 | CXCR2 (0.54) | CXCR2CXCR1CCR7 | |
| SCHEMBL13407249 | 0.84 | CXCR2 (0.71) | CXCR2CXCR1CCR7 | |
| SCHEMBL13440327 | 0.84 | CXCR2 (0.71) | CXCR2CXCR1CCR7 | |
| SCHEMBL13440143 | 0.83 | CXCR2 (0.56) | CXCR2CXCR1CCR7 | |
| SCHEMBL13407293 | 0.83 | CXCR2 (0.56) | CXCR2CXCR1CCR7 | |
| SCHEMBL13948143 | 0.80 | CXCR1 (0.54) | CXCR2CXCR1CCR7 | |
| SCHEMBL13439952 | 0.79 | CXCR1 (0.54) | CXCR2CXCR1CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691856-B2 | Thiadiazoledioxides and thiadiazoleoxides as CXC- and CC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2010-04-06 | — | — | US | disclosed |