Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13389375 | 1.00 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3PRMT5WDR77 | |
| SCHEMBL13389337 | 0.86 | PRMT5 (0.45) | SLC6A2SLC6A4SLC6A3PRMT5WDR77 | |
| SCHEMBL13389509 | 0.86 | PRMT5 (0.45) | SLC6A2SLC6A4SLC6A3PRMT5WDR77 | |
| SCHEMBL13389890 | 0.86 | PRMT5 (0.45) | SLC6A2SLC6A4SLC6A3PRMT5WDR77 | |
| SCHEMBL13408018 | 0.82 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3PRMT5WDR77 | |
| SCHEMBL13389383 | 0.82 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3PRMT5WDR77 | |
| SCHEMBL13389492 | 0.81 | PRMT5 (0.46) | SLC6A2SLC6A4SLC6A3PRMT5WDR77 | |
| SCHEMBL13389252 | 0.79 | PRMT5 (0.44) | SLC6A2SLC6A4SLC6A3PRMT5WDR77 | |
| SCHEMBL13389517 | 0.79 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3PRMT5WDR77 | |
| SCHEMBL13389569 | 0.79 | SLC6A2 (0.53) | SLC6A2SLC6A4SLC6A3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7705153-B2 | Bipiperdine derivatives useful as CCR3 antagonists | SCHERING CORPORATION (US) | 2010-04-27 | — | — | US | disclosed |
| EP-1725235-B1 | PIPERIDINE DERIVATIVES USEFUL AS CCR3 ANTAGONISTS | SCHERING CORP (US) | 2009-04-15 | — | — | EP | disclosed |