SCHEMBL13407644

SCHEMBL13407644

O=C(c1cc(O)nc2ccccc12)N1CCC(N2CC[C@H](Cc3ccc(Cl)c(Cl)c3)[C@H](CO)C2)CC1

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CCR3 P51677 20/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13389698 1.00 CCR3 (0.63) CCR3
SCHEMBL13407826 0.90 CCR3 (0.61) CCR3
SCHEMBL13389457 0.90 CCR3 (0.61) CCR3
SCHEMBL13389790 0.89 CCR3 (0.65) CCR3
SCHEMBL13407856 0.89 CCR3 (0.60) CCR3
SCHEMBL13407873 0.89 CCR3 (0.65) CCR3
SCHEMBL13389694 0.89 CCR3 (0.60) CCR3
SCHEMBL13389750 0.88 CCR3 (0.59) CCR3
SCHEMBL13389401 0.88 CCR3 (0.60) CCR3
SCHEMBL13407821 0.88 CCR3 (0.59) CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7705153-B2 Bipiperdine derivatives useful as CCR3 antagonists SCHERING CORPORATION (US) 2010-04-27 — — US disclosed
Send feedback