Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.40 |
| ▸ | PNP | P00491 | 8/20 | 0.36 |
| ▸ | TYMS | P04818 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14626183 | 0.80 | PNP (0.36) | TLR7PNPTYMS | |
| SCHEMBL13408670 | 0.80 | PNP (0.55) | PNP | |
| SCHEMBL280482 | 0.79 | PNP (0.36) | TLR7PNP | |
| SCHEMBL3308717 | 0.76 | PNP (0.53) | TLR7PNP | |
| SCHEMBL260736 | 0.76 | PNP (0.53) | TLR7PNP | |
| SCHEMBL258829 | 0.76 | PNP (0.53) | TLR7PNP | |
| SCHEMBL260738 | 0.76 | PNP (0.53) | TLR7PNP | |
| SCHEMBL264086 | 0.71 | PNP (0.39) | PNP | |
| SCHEMBL3300370 | 0.71 | PNP (0.39) | PNP | |
| SCHEMBL264417 | 0.68 | CYP1A2 (0.41) | PNPTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8344132-B2 | Methods for the preparation of 9-deazapurine derivatives | BioCryst Pharmaceticals, Inc. (US) | 2013-01-01 | — | — | US | disclosed |
| US-20100093991-A1 | METHODS FOR THE PREPARATION OF 9-DEAZAPURINE DERIVATIVES | BIO CRYST PHARMACEUTICALS , INC. (US) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093991-A1 | METHODS FOR THE PREPARATION OF 9-DEAZAPURINE DERIVATIVES | DPYD, TYMP, UNG | TLR7 2129/4885PNP 8/4885TYMS 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.