Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13412235 | 0.89 | ELANE (0.63) | ELANECYP3A4CYP2C9 | |
| SCHEMBL8344209 | 0.87 | ELANE (0.75) | ELANECYP3A4CYP2C9 | |
| SCHEMBL2896528 | 0.86 | ELANE (0.79) | ELANECYP3A4CYP2C9 | |
| SCHEMBL8344045 | 0.85 | ELANE (0.64) | ELANECYP3A4CYP2C9 | |
| SCHEMBL13412238 | 0.84 | ELANE (0.66) | ELANECYP3A4CYP2C9 | |
| SCHEMBL8347811 | 0.84 | ELANE (0.66) | ELANECYP3A4CYP2C9 | |
| SCHEMBL8345575 | 0.83 | ELANE (0.63) | ELANECYP3A4CYP2C9 | |
| SCHEMBL13412232 | 0.83 | ELANE (0.73) | ELANECYP3A4CYP2C9 | |
| SCHEMBL13412234 | 0.83 | ELANE (0.61) | ELANECYP3A4CYP2C9 | |
| SCHEMBL14899943 | 0.83 | ELANE (0.63) | ELANECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687510-B2 | Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes | BAYER HEALTHCARE AG (DE) | 2010-03-30 | — | — | US | disclosed |
| US-7687510-B2 | Pyrimidinone derivatives as therapeutic agents against acute and chronic inflammatory, ischaemic and remodelling processes | BAYER HEALTHCARE AG (DE) | 2010-03-30 | — | — | US | disclosed |