SCHEMBL13412690

SCHEMBL13412690

COc1ccc(C=C(C#N)C(=O)Nc2ccccc2)cc1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.74
▸ KMT2A Q03164 6/20 0.74
▸ MEN1 O00255 5/20 0.74
▸ ALDH1A1 P00352 4/20 0.74
▸ SMN1; SMN2 Q16637 3/20 0.74
▸ MAPK1 P28482 2/20 0.74
▸ KDM4E B2RXH2 2/20 0.74
▸ EGFR P00533 2/20 0.74
▸ PSMD14 O00487 1/20 0.74
▸ RGS12 O14924 1/20 0.74
▸ GMNN O75496 1/20 0.74
▸ LMNA P02545 1/20 0.74
▸ ERBB2 P04626 1/20 0.74
▸ TP53 P04637 1/20 0.74
▸ CYP1A2 P05177 1/20 0.74
▸ CYP3A4 P08684 1/20 0.74
▸ CYP2D6 P10635 1/20 0.74
▸ PKM P14618 1/20 0.74
▸ HPGD P15428 1/20 0.74
▸ ALOX15 P16050 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1704988 0.85 EGFR (1.00) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL5909179 0.85 EGFR (1.00) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL30555674 0.85 EGFR (1.00) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL29766990 0.85 EGFR (1.00) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL10615589 0.83 KMT2A (0.72) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL10615583 0.83 KMT2A (0.72) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL11801440 0.82 EGFR (0.68) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL11801445 0.82 EGFR (0.68) MAPTKMT2AMEN1ALDH1A1KDM4E
SCHEMBL13633381 0.82 CA12 (0.71) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL9573610 0.81 KMT2A (0.68) MAPTKMT2AMEN1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7687229-B2 Silver halide color photographic light-sensitive material and image forming method FUJIFILM CORPORATION (JP) 2010-03-30 — — US disclosed
US-20070298348-A1 Silver Halide Color Photographic Light-Sensitive Material and Image Forming Method FUJIFILM CORPORATION (JP) 2007-12-27 — — US disclosed
US-7189501-B2 Silver halide color photographic photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-13 — — US disclosed
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