Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | HMGCR | P04035 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13412971 | 0.96 | PTPN1 (0.53) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL13413063 | 0.96 | PTPN1 (0.53) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL14263475 | 0.89 | PTPN1 (0.58) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL22022507 | 0.89 | PTPN1 (0.58) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL8829597 | 0.89 | PTPN1 (0.58) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL12352422 | 0.89 | PTPN1 (0.58) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL5981982 | 0.89 | PTPN1 (0.61) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL5981979 | 0.89 | PTPN1 (0.61) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL13871572 | 0.89 | PTPN1 (0.58) | TSHRPTPN1USP2KMT2AMEN1 | |
| SCHEMBL4849838 | 0.89 | PTPN1 (0.58) | TSHRPTPN1USP2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674778-B2 | Oligonucleotides comprising a conjugate group linked through a C5-modified pyrimidine | ALNYLAM PHARMACEUTICALS (US) | 2010-03-09 | — | — | US | disclosed |