Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 5/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13413505 | 0.90 | NPC1 (0.57) | NPC1POLBRAB9AAPPSMN1; SMN2 | |
| SCHEMBL13413555 | 0.89 | APP (0.46) | NPC1POLBRAB9AAPPTUBB1 | |
| SCHEMBL13413542 | 0.87 | FFAR1 (0.45) | NPC1POLBRAB9ATUBB1TUBB4A | |
| SCHEMBL13413469 | 0.87 | MAOB (0.48) | NPC1POLBRAB9ATUBB1TUBB4A | |
| SCHEMBL13448124 | 0.87 | SLC2A1 (0.47) | NPC1POLBRAB9AAPPTUBB1 | |
| SCHEMBL6489381 | 0.85 | NPC1 (0.56) | NPC1POLBRAB9AAPPTUBB1 | |
| SCHEMBL21377514 | 0.85 | NPC1 (0.63) | NPC1POLBRAB9AAPPTUBB1 | |
| SCHEMBL13413544 | 0.85 | C5AR1 (0.41) | NPC1POLBRAB9AAPPSMN1; SMN2 | |
| SCHEMBL13448412 | 0.83 | APP (0.47) | NPC1POLBRAB9AAPPTUBB1 | |
| SCHEMBL13413545 | 0.82 | NR5A1 (0.48) | NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671033-B2 | Amphiphilic dendritic dipeptides and their self-assembly into helical pores | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-03-02 | — | — | US | disclosed |
| US-7671033-B2 | Amphiphilic dendritic dipeptides and their self-assembly into helical pores | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-03-02 | — | — | US | disclosed |