Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 10/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 9/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13420661 | 0.94 | P2RY12 (0.45) | P2RY12CHRM3PPARG | |
| SCHEMBL13420659 | 0.94 | CHRM3 (0.46) | P2RY12CHRM3PPARG | |
| SCHEMBL13420645 | 0.94 | P2RY12 (0.46) | P2RY12CHRM3PPARG | |
| SCHEMBL13420655 | 0.94 | CHRM3 (0.45) | P2RY12CHRM3PPARG | |
| SCHEMBL13422903 | 0.92 | CHRM3 (0.43) | P2RY12CHRM3PPARG | |
| SCHEMBL13420668 | 0.91 | P2RY12 (0.48) | P2RY12CHRM3PPARG | |
| SCHEMBL13420647 | 0.91 | CHRM3 (0.49) | P2RY12CHRM3PPARG | |
| SCHEMBL13419807 | 0.91 | CHRM3 (0.47) | P2RY12CHRM3 | |
| SCHEMBL13420671 | 0.90 | CHRM3 (0.49) | P2RY12CHRM3PPARG | |
| SCHEMBL13419870 | 0.88 | CHRM3 (0.40) | P2RY12CHRM3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7674803-B2 | Thiazolypiperidine derivatives as MTP inhibitors | MERCK PATENT GMBH (DE) | 2010-03-09 | — | — | US | disclosed |
| US-7674803-B2 | Thiazolypiperidine derivatives as MTP inhibitors | MERCK PATENT GMBH (DE) | 2010-03-09 | — | — | US | disclosed |