Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 10/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 8/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2359696 | 0.88 | TYK2 (0.42) | TYK2STAT3CSNK2A2 | |
| SCHEMBL13421758 | 0.85 | CSNK2A2 (0.48) | TYK2CCNE1CDK2FLT3CSNK2A2 | |
| SCHEMBL13421527 | 0.82 | CSNK2A2 (0.45) | TYK2CCNE1CDK2FLT3CSNK2A2 | |
| SCHEMBL13421764 | 0.82 | TYK2 (0.54) | TYK2CCNE1CDK2FLT3STAT3 | |
| SCHEMBL13421865 | 0.81 | CSNK2A2 (0.47) | TYK2CCNE1CDK2FLT3CSNK2A2 | |
| SCHEMBL13421868 | 0.80 | TYK2 (0.46) | TYK2CCNE1CDK2FLT3STAT3 | |
| SCHEMBL13421329 | 0.79 | CSNK2A2 (0.52) | TYK2CCNE1CDK2FLT3CSNK2A2 | |
| SCHEMBL13421866 | 0.78 | CSNK2A2 (0.41) | TYK2CCNE1CDK2FLT3CSNK2A2 | |
| SCHEMBL13421339 | 0.77 | TYK2 (0.47) | TYK2CCNE1CDK2FLT3STAT3 | |
| SCHEMBL13421860 | 0.76 | TYK2 (0.60) | TYK2CCNE1CDK2FLT3STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042699-A1 | IMIDAZOPYRIDAZINECARBONITRILES USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-04-15 | — | — | WO | disclosed |