Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 9/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.49 |
| ▸ | CDK2 | P24941 | 9/20 | 0.49 |
| ▸ | FLT3 | P36888 | 9/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2358675 | 0.85 | TYK2 (0.47) | TYK2CCNE1CDK2FLT3SYK | |
| SCHEMBL13421860 | 0.81 | TYK2 (0.60) | TYK2CCNE1CDK2FLT3STAT3 | |
| SCHEMBL13421534 | 0.81 | TYK2 (0.53) | TYK2CCNE1CDK2FLT3STAT3 | |
| SCHEMBL13421550 | 0.79 | TYK2 (0.60) | TYK2CCNE1CDK2FLT3STAT3 | |
| SCHEMBL13422025 | 0.79 | TYK2 (0.55) | TYK2CCNE1CDK2FLT3STAT3 | |
| SCHEMBL13421559 | 0.78 | TYK2 (0.52) | TYK2CCNE1CDK2FLT3STAT3 | |
| SCHEMBL13421591 | 0.78 | TYK2 (0.52) | TYK2CCNE1CDK2FLT3STAT3 | |
| SCHEMBL13421343 | 0.76 | TYK2 (0.57) | TYK2CCNE1CDK2FLT3STAT3 | |
| SCHEMBL13421329 | 0.76 | CSNK2A2 (0.52) | TYK2CCNE1CDK2FLT3 | |
| SCHEMBL13421365 | 0.76 | TYK2 (0.52) | TYK2CCNE1CDK2FLT3STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042699-A1 | IMIDAZOPYRIDAZINECARBONITRILES USEFUL AS KINASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-04-15 | — | — | WO | disclosed |