Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.53 |
| ▸ | CHRNG | P07510 | 1/20 | 0.53 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.53 |
| ▸ | CHRND | Q07001 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL634070 | 0.86 | SLC6A2 (0.55) | PARP1HDAC8HDAC6SLC6A2SLC6A3 | |
| SCHEMBL17762880 | 0.82 | PARP1 (0.50) | PARP1HDAC8HDAC6SLC6A2SLC6A3 | |
| SCHEMBL19707514 | 0.82 | TDP1 (0.51) | PARP1HDAC8HDAC6SLC6A2SLC6A3 | |
| SCHEMBL25247146 | 0.82 | PARP1 (0.59) | PARP1HDAC8HDAC6SLC6A2SLC6A3 | |
| SCHEMBL585998 | 0.82 | PARP1 (0.59) | PARP1HDAC8HDAC6SLC6A2SLC6A3 | |
| SCHEMBL29923066 | 0.82 | PARP1 (0.59) | PARP1HDAC8HDAC6SLC6A2SLC6A3 | |
| SCHEMBL1305879 | 0.80 | SLC6A2 (0.57) | PARP1HDAC8HDAC6SLC6A2SLC6A3 | |
| SCHEMBL15007483 | 0.80 | SLC6A2 (0.57) | PARP1HDAC8HDAC6SLC6A2SLC6A3 | |
| SCHEMBL8507979 | 0.80 | PARP1 (0.57) | PARP1HDAC8HDAC6SLC6A2SLC6A3 | |
| SCHEMBL18068936 | 0.80 | SLC6A2 (0.57) | PARP1HDAC8HDAC6SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |