Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1879028 | 0.93 | ACE2 (0.55) | BLMGABRR1CYP1A2LTA4HACE2 | |
| SCHEMBL1875958 | 0.93 | ACE2 (0.55) | BLMGABRR1CYP1A2LTA4HACE2 | |
| SCHEMBL17285499 | 0.89 | BLM (0.73) | BLMGABRR1CYP1A2LTA4HACE2 | |
| SCHEMBL233225 | 0.89 | BLM (0.73) | BLMGABRR1CYP1A2LTA4HACE2 | |
| SCHEMBL6381204 | 0.87 | GABRR1 (0.59) | BLMGABRR1CYP1A2LTA4HACE2 | |
| SCHEMBL16330413 | 0.84 | BLM (0.65) | BLMGABRR1CYP1A2LTA4HACE2 | |
| SCHEMBL7179523 | 0.84 | BLM (0.65) | BLMGABRR1CYP1A2LTA4HACE2 | |
| SCHEMBL28488630 | 0.83 | BLM (0.59) | BLMGABRR1CYP1A2LTA4HACE2 | |
| SCHEMBL19814941 | 0.82 | TP53 (0.43) | BLMGABRR1CYP1A2TP53GPR84 | |
| SCHEMBL276749 | 0.82 | BLM (0.86) | BLMGABRR1CYP1A2LTA4HACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2644588-A2 | Biomarkers for diagnosing multiple sclerosis, and methods thereof | Phenomenome Discoveries Inc. (CA) | 2013-10-02 | — | — | EP | disclosed |
| US-20100062472-A1 | BIOMARKERS FOR DIAGNOSING MULTIPLE SCLEROSIS, AND METHODS THEREOF | PHENOMENOME DISCOVERIES INC. (CA) | 2010-03-11 | — | — | US | disclosed |
| US-20100062472-A1 | BIOMARKERS FOR DIAGNOSING MULTIPLE SCLEROSIS, AND METHODS THEREOF | PHENOMENOME DISCOVERIES INC. (CA) | 2010-03-11 | — | — | US | disclosed |