Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.56 |
| ▸ | PPARA | Q07869 | 11/20 | 0.56 |
| ▸ | PPARG | P37231 | 8/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13433439 | 0.91 | PTPN11 (0.50) | PPARDPPARAPPARGPTPN11 | |
| SCHEMBL13433429 | 0.89 | PPARD (0.47) | PPARDPPARAPPARG | |
| SCHEMBL13433442 | 0.88 | PPARD (0.72) | PPARDPPARAPPARG | |
| SCHEMBL3413388 | 0.88 | PPARD (0.72) | PPARDPPARAPPARGPTPN11 | |
| SCHEMBL3419318 | 0.86 | PPARD (0.62) | PPARDPPARAPPARG | |
| SCHEMBL13433443 | 0.85 | PTPN11 (0.49) | PPARDPPARAPPARGPTPN11 | |
| SCHEMBL13460797 | 0.85 | PPARD (0.55) | PPARDPPARAPPARG | |
| SCHEMBL3419425 | 0.83 | PPARD (0.71) | PPARDPPARAPPARG | |
| SCHEMBL3414033 | 0.83 | PPARD (0.62) | PPARDPPARAPPARG | |
| SCHEMBL13433449 | 0.82 | PPARG (0.47) | PPARDPPARAPPARGPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |