Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGFR | P43088 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3416365 | 0.92 | CYP1A2 (0.50) | MEN1KMT2AFFAR1PPARGGPR34 | |
| SCHEMBL3416680 | 0.90 | PLA2G4B (0.45) | FFAR1PPARDNR1H4AKR1B1FFAR4 | |
| SCHEMBL3416099 | 0.89 | FFAR1 (0.52) | FFAR1PPARGPPARDPTGER3AKR1B1 | |
| SCHEMBL3418795 | 0.87 | PPARD (0.47) | MEN1KMT2APPARDNR1H4TBXA2R | |
| SCHEMBL3411776 | 0.87 | MEN1 (0.43) | MEN1KMT2AFFAR1PPARGPPARD | |
| SCHEMBL3413257 | 0.85 | PPARD (0.48) | FFAR1PPARGPPARDTBXA2RPTGER1 | |
| SCHEMBL3411834 | 0.84 | NR1H2 (0.55) | FFAR1PPARDGPR34FFAR4RXRA | |
| SCHEMBL3411927 | 0.83 | SCN9A (0.45) | PPARDNR1H4TBXA2RPTGER1RXRA | |
| SCHEMBL3416517 | 0.82 | NR1H2 (0.53) | MEN1KMT2AFFAR1NR1H4AKR1B1 | |
| SCHEMBL3416662 | 0.82 | FFAR1 (0.60) | FFAR1PPARGPPARDRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |
| US-7687664-B2 | Carboxylic acid derivative, a salt thereof or an ester of them, and medicament comprising it | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-30 | — | — | US | disclosed |