Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 19/20 | 0.65 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1713034 | 0.92 | PDK2 (0.75) | PDK2 | |
| SCHEMBL1712256 | 0.79 | PDK2 (1.00) | PDK2 | |
| SCHEMBL1712458 | 0.76 | PDK2 (0.76) | PDK2 | |
| SCHEMBL16139289 | 0.76 | PDK2 (0.76) | PDK2 | |
| SCHEMBL12460645 | 0.75 | PDK2 (1.00) | PDK2 | |
| SCHEMBL13128355 | 0.74 | PDK2 (1.00) | PDK2 | |
| SCHEMBL13128000 | 0.74 | PDK2 (1.00) | PDK2 | |
| SCHEMBL1712238 | 0.72 | PDK2 (0.76) | PDK2 | |
| SCHEMBL13128336 | 0.72 | PDK2 (0.72) | PDK2 | |
| SCHEMBL13128356 | 0.71 | PDK2 (1.00) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010041748-A1 | FLUORENE COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | 日本たばこ産業株式会社 (JP) | 2010-04-15 | — | — | WO | disclosed |