Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 2/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17233403 | 0.88 | TSHR (0.46) | TSHRTP53HSD17B10MGAMGAA | |
| SCHEMBL1484429 | 0.82 | TSHR (0.40) | TSHRTP53HSD17B10MGAMGAA | |
| SCHEMBL15453370 | 0.82 | MGAM (0.48) | TSHRTP53HSD17B10MGAMGAA | |
| SCHEMBL16753659 | 0.81 | GAA (0.48) | TSHRTP53HSD17B10MGAMGAA | |
| SCHEMBL594992 | 0.80 | TSHR (0.46) | TSHRTP53HSD17B10MGAMGAA | |
| SCHEMBL12943053 | 0.80 | — | — | |
| SCHEMBL15453519 | 0.80 | TSHR (0.45) | TSHRTP53KMT2ALMNA | |
| SCHEMBL1132780 | 0.80 | TSHR (0.39) | TSHRTP53HSD17B10MGAMGAA | |
| SCHEMBL7515086 | 0.80 | GAA (0.46) | TSHRHSD17B10MGAMGAASI | |
| SCHEMBL16314979 | 0.80 | TSHR (0.50) | TSHRTP53HSD17B10MGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8450491-B2 | Method for the preparation of montelukast acid and sodium salt thereof in amorphous form | MOREPEN LABORATORIES LIMITED (IN) | 2013-05-28 | — | — | US | disclosed |
| US-8426599-B2 | Method for preparation of Montelukast acid in ionic liquid medium | HANMI SCIENCE CO., LTD (KR) | 2013-04-23 | — | — | US | disclosed |
| WO-2010036048-A2 | METHOD FOR PREPARING MONTELUKAST SODIUM SALTS | 주식회사 엘지생명과학 (KR) | 2010-04-01 | — | — | WO | disclosed |