⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533681 | 1.00 | — | — | |
| SCHEMBL3533683 | 1.00 | — | — | |
| SCHEMBL7641296 | 0.88 | — | — | |
| SCHEMBL7641293 | 0.88 | — | — | |
| SCHEMBL879473 | 0.81 | — | — | |
| SCHEMBL12217032 | 0.75 | — | — | |
| SCHEMBL1470402 | 0.75 | — | — | |
| SCHEMBL24656090 | 0.73 | — | — | |
| SCHEMBL20782996 | 0.73 | — | — | |
| SCHEMBL9336557 | 0.73 | CYP1A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9085538-B2 | Process for the preparation of key intermediates for the synthesis of statins or pharmaceutically acceptable salts thereof | LEK PHARMACEUTICALS D.D. (SI) | 2015-07-21 | — | — | US | disclosed |
| US-20140051854-A1 | PROCESS FOR THE PREPARATION OF KEY INTERMEDIATES FOR THE SYNTHESIS OF STATINS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LEK PHARMACEUTICALS D.D. (SI) | 2014-02-20 | — | — | US | disclosed |
| US-7671231-B2 | L-allysine acetal prepared by contacting a 2-butene acetal with a hydroformylation catalyst and synthesis gas to prepare aldehyde mixture; contacting with an enantioselective hydrolase in the presence of water and hydrocyanic acid/ammonia; separation from branched derivatives | LLOYD MICHAEL C | 2010-03-02 | — | — | US | disclosed |
| US-20080227851-A1 | LAULIMALIDE AND LAULIMALIDE ANALOGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-09-18 | — | — | US | disclosed |
| WO-2007084545-A1 | PROCESS FOR MAKING AMINO ACIDS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-07-26 | — | — | WO | disclosed |
| US-20070166806-A1 | Process for making amino acids | LLOYD MICHAEL C | 2007-07-19 | — | — | US | disclosed |
| US-20070166806-A1 | Process for making amino acids | LLOYD MICHAEL C | 2007-07-19 | — | — | US | disclosed |