Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13435750 | 0.92 | ADRB3 (0.35) | F2F10PRSS1ADRB3ADRA2B | |
| SCHEMBL13435939 | 0.91 | ADRB3 (0.35) | F2F10PRSS1ADRB3ADRA2B | |
| SCHEMBL13435935 | 0.91 | ADRB3 (0.35) | F2F10PRSS1ADRB3ADRA2B | |
| SCHEMBL13435751 | 0.89 | ADRB3 (0.36) | F2F10PRSS1ADRB3ADRA2B | |
| SCHEMBL8237405 | 0.87 | F2 (0.39) | F2F10PRSS1ADRB3ADRA2B | |
| SCHEMBL7999967 | 0.86 | ADRB3 (0.42) | F2F10PRSS1ADRB3ADRA2B | |
| SCHEMBL1645865 | 0.86 | ADRB3 (0.42) | F2F10PRSS1ADRB3ADRA2B | |
| SCHEMBL8378473 | 0.86 | ADRB3 (0.42) | F2F10PRSS1ADRB3ADRA2B | |
| SCHEMBL1645862 | 0.86 | ADRB3 (0.42) | F2F10PRSS1ADRB3ADRA2B | |
| SCHEMBL8237408 | 0.86 | ADRB3 (0.42) | F2F10PRSS1ADRB3ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177523-A1 | Novel macrocyclic inhibitors of hepatitis c virus replication | Intermune, Inc. (US) | 2010-04-21 | — | — | EP | disclosed |