SCHEMBL13438342

SCHEMBL13438342

NC(=O)CC[C@@H](N)Cc1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.53
CA2 P00918 1/20 0.50
TAAR1 Q96RJ0 3/20 0.48
SLC6A2 P23975 1/20 0.48
OPRK1 P41145 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10098450 1.00 SLC7A5 (0.53) SLC7A5CA2TAAR1SLC6A2OPRK1
SCHEMBL16103714 1.00 SLC7A5 (0.53) SLC7A5CA2TAAR1SLC6A2OPRK1
SCHEMBL29074770 0.86 SLC7A5 (0.58) SLC7A5CA2TAAR1SLC6A2OPRK1
SCHEMBL288170 0.86 SLC7A5 (0.58) SLC7A5CA2TAAR1SLC6A2OPRK1
SCHEMBL932261 0.86 SLC7A5 (0.58) SLC7A5CA2TAAR1SLC6A2OPRK1
SCHEMBL13452451 0.84 EPHX1 (0.57) SLC7A5
SCHEMBL20717804 0.84 EPHX1 (0.57) SLC7A5
Hydrochloric Acid SCHEMBL20704533 0.82 EPHX1 (0.55) SLC7A5
Hydrochloric Acid SCHEMBL20704531 0.82 EPHX1 (0.55) SLC7A5
SCHEMBL20707602 0.81 SLC7A5 (0.56) SLC7A5CA2TAAR1SLC6A2OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7691899-B2 Urea oligomers, the preparation method thereof and pharmaceutical composition containing same CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-04-06 US disclosed