Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 12/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11940990 | 1.00 | MAPT (0.51) | MAPTLRRK2BRD4RAB9A | |
| SCHEMBL11935563 | 1.00 | MAPT (0.51) | MAPTLRRK2BRD4RAB9A | |
| SCHEMBL11934800 | 1.00 | MAPT (0.51) | MAPTLRRK2BRD4RAB9A | |
| SCHEMBL11940094 | 0.85 | POLB (0.36) | MAPTBRD4 | |
| SCHEMBL11940092 | 0.85 | POLB (0.36) | MAPTBRD4 | |
| SCHEMBL11935557 | 0.85 | POLB (0.36) | MAPTBRD4 | |
| SCHEMBL11935568 | 0.85 | POLB (0.36) | MAPTBRD4 | |
| SCHEMBL13105584 | 0.85 | MAPT (0.39) | MAPTBRD4 | |
| SCHEMBL11935531 | 0.85 | MAPT (0.39) | MAPTBRD4 | |
| SCHEMBL11940093 | 0.85 | JAK2 (0.40) | MAPTLRRK2BRD4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150507-B2 | Amine derivative having NPY Y5 receptor antagonistic activity | SHIONOGI & CO., LTD. (JP) | 2015-10-06 | — | — | US | disclosed |
| US-20100063027-A1 | Amine Derivative Having NPY Y5 Receptor Antagonistic Activity | SHIONOGI & CO., LTD. (JP) | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063027-A1 | Amine Derivative Having NPY Y5 Receptor Antagonistic Activity | NPY5R, NPY1R, NPY2R | MAPT 3293/4885LRRK2 1529/4885BRD4 1136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.