Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13406300 | 1.00 | CXCR1 (0.35) | CXCR1CXCR2GAA | |
| SCHEMBL13406865 | 0.89 | CXCR1 (0.35) | CXCR1CXCR2GAA | |
| SCHEMBL13439855 | 0.81 | CXCR1 (0.36) | CXCR1CXCR2 | |
| SCHEMBL13439911 | 0.77 | MEN1 (0.35) | GAA | |
| SCHEMBL13440325 | 0.73 | CXCR1 (0.40) | CXCR1CXCR2 | |
| SCHEMBL13406303 | 0.73 | CXCR1 (0.40) | CXCR1CXCR2 | |
| SCHEMBL13406868 | 0.71 | — | — | |
| SCHEMBL13406913 | 0.69 | CXCR2 (0.68) | CXCR1CXCR2 | |
| SCHEMBL13440321 | 0.69 | CXCR2 (0.43) | CXCR1CXCR2 | |
| SCHEMBL13947680 | 0.69 | CXCR2 (0.43) | CXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691856-B2 | Thiadiazoledioxides and thiadiazoleoxides as CXC- and CC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2010-04-06 | — | — | US | disclosed |
| EP-1551818-B1 | THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS | SCHERING CORP (US) | 2009-02-04 | — | — | EP | disclosed |