Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.56 |
| ▸ | CXCR1 | P25024 | 19/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13406893 | 0.89 | CXCR2 (0.68) | CXCR2CXCR1 | |
| SCHEMBL13440165 | 0.88 | CXCR1 (0.55) | CXCR2CXCR1 | |
| SCHEMBL13407032 | 0.87 | CXCR2 (0.70) | CXCR2CXCR1 | |
| SCHEMBL13405673 | 0.86 | CXCR1 (0.70) | CXCR2CXCR1 | |
| SCHEMBL13405670 | 0.86 | CXCR1 (0.70) | CXCR2CXCR1 | |
| SCHEMBL13406890 | 0.84 | CXCR2 (0.71) | CXCR2CXCR1 | |
| SCHEMBL13439877 | 0.84 | CXCR2 (0.52) | CXCR2CXCR1 | |
| SCHEMBL13227096 | 0.83 | CXCR2 (0.58) | CXCR2CXCR1 | |
| SCHEMBL13227286 | 0.82 | CXCR1 (0.60) | CXCR2CXCR1 | |
| SCHEMBL13947554 | 0.81 | CXCR2 (0.53) | CXCR2CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691856-B2 | Thiadiazoledioxides and thiadiazoleoxides as CXC- and CC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2010-04-06 | — | — | US | disclosed |