SCHEMBL1344036

SCHEMBL1344036

Clc1ncncc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29460951 1.00
Hydrochloric Acid SCHEMBL1938553 0.97
SCHEMBL691236 0.72
SCHEMBL28623317 0.72
SCHEMBL30660135 0.72
Hydrochloric Acid SCHEMBL1937524 0.70
Ammonia Solution, Strong SCHEMBL28196082 0.70
SCHEMBL1463005 0.69 PDE4A (0.35)
SCHEMBL20399898 0.69 RPS6KA5 (0.36)
SCHEMBL17581239 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 856 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119390645-A Dehalogenation method for reducing N heteroaryl halide by using hydrosilane 浙江科技大学 2025-02-07 CN claimed
CN-116253687-A Diaryl pyrimidine compound and preparation method and application thereof 复旦大学 2023-06-13 CN claimed
CN-101230036-A Method for preparing heterocyclic aryl-aryl biphenyl compounds UNIV ZHEJIANG (CN) 2008-07-30 CN claimed
EP-4741386-A1 PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF Jiangsu Yahong Meditech Co., Ltd. (CN) 2026-05-13 EP disclosed
EP-4739307-A2 TARGETED EPIGENETIC THERAPIES FOR DISORDERS OF PROGRANULIN DEFICIENCY The General Hospital Corporation (US) 2026-05-13 EP disclosed
US-12583870-B2 Azaheteroaryl compound and application thereof SHANGHAI BLUERAY BIOPHARMA CO., LTD. (CN) 2026-03-24 US disclosed
US-12577228-B2 Dihydrocyclopenta-isoquinoline-sulfonamide derivatives compounds UCB Biopharma SRL (BE) 2026-03-17 US disclosed
EP-4081296-B1 DIHYDROCYCLOPENTA-ISOQUINOLINE-SULFONAMIDE DERIVATIVES COMPOUNDS UCB Biopharma SRL (BE) 2026-02-11 EP disclosed
EP-4076460-B1 1,4-DIHYDRO-2H-SPIRO[ISOQUINOLINE-3,4'-PIPERIDINE DERIVATIVES AS PRMT5 INHIBITORS FOR THE TREATMENT OF CANCER MERCK SHARP & DOHME LLC (US) 2026-01-21 EP disclosed
EP-4676914-A1 MODULATORS OF SORTILIN ACTIVITY Vesper Bio Aps (DK) 2026-01-14 EP disclosed
US-20250388583-A1 COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION ENGINE BIOSCIENCES PTE LTD (SG) 2025-12-25 US disclosed
WO-1997037978-A1 4-SUBSTITUTED 5-POLYCYCLYLPYRIMIDINE HERBICIDES DOWELANCO (US) 1997-10-16 WO disclosed
US-4736037-A 2-halo-aryl-pyridinemethanols with analgesic or antiinflammatory activity LACER, S.A. (ES) 1988-04-05 US disclosed
US-4614833-A 2-halo-pyridines LACER, S.A. (ES) 1986-09-30 US disclosed
EP-0065757-B1 1-(3-HALO-2-PYRIDINYL)PIPERAZINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM MERCK & CO. INC. (US) 1985-01-09 EP disclosed
US-4456604-A ANTIDEPRESSANTS MERCK & CO., INC. (US) 1984-06-26 US disclosed
EP-0032516-B1 NEW 2-HALO-PYRIDINES, THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS LACER, S.A. (ES) 1984-05-02 EP disclosed
EP-0065757-A1 1-(3-Halo-2-pyridinyl)piperazines, processes for their preparation and pharmaceutical composition containing them MERCK & CO. INC. (US) 1982-12-01 EP disclosed
EP-0032516-A1 New 2-halo-pyridines, their production and pharmaceutical compositions LACER, S.A. (ES) 1981-07-29 EP disclosed
US-4052508-A TRANQUILIZER, MUSCLE RELAXANT, ANTICONVULSANT, ANTIPARKINSON MERCK & CO., INC. (US) 1977-10-04 US disclosed