Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 7/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL21273381 | 0.99 | KAT2B (0.61) | KAT2BPOLBMAPTPKMKDM4E | |
| SCHEMBL2228520 | 0.95 | KAT2B (0.66) | KAT2BPOLBMAPTPKMKDM4E | |
| SCHEMBL30413993 | 0.93 | KAT2B (0.64) | KAT2BPOLBMAPTPKMKDM4E | |
| SCHEMBL2228171 | 0.93 | KAT2B (0.64) | KAT2BPOLBMAPTPKMKDM4E | |
| SCHEMBL4557828 | 0.93 | KAT2B (0.64) | KAT2BPOLBMAPTPKMKDM4E | |
| SCHEMBL17923845 | 0.93 | KAT2B (0.64) | KAT2BPOLBMAPTPKMKDM4E | |
| Hydrochloric Acid SCHEMBL4699216 | 0.92 | KAT2B (0.65) | KAT2BPOLBMAPTPKMKDM4E | |
| SCHEMBL10622798 | 0.90 | KAT2B (0.72) | KAT2BPOLBMAPTPKMKDM4E | |
| SCHEMBL8147273 | 0.87 | MAPT (0.65) | KAT2BPOLBMAPTPKMKDM4E | |
| SCHEMBL502704 | 0.84 | KAT2B (0.58) | KAT2BPOLBMAPTPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11680264-B2 | Methods of modulating melanosome pH and melanin level in cells | CORNELL UNIVERSITY (US) | 2023-06-20 | — | — | US | disclosed |
| US-10401361-B2 | Intracellular organelle peptide targeted enzyme substrates | MARKER GENE TECHNOLOGIES, INC. (US) | 2019-09-03 | — | — | US | disclosed |
| US-20190256856-A1 | METHODS OF MODULATING MELANOSOME PH AND MELANIN LEVEL IN CELLS | CORNELL UNIVERSITY (US) | 2019-08-22 | — | — | US | disclosed |
| US-20180120317-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | MARKER GENE TECHNOLOGIES, INC. | 2018-05-03 | — | — | US | disclosed |
| WO-2018006039-A1 | METHODS OF MODULATING MELANOSOME PH AND MELANIN LEVEL IN CELLS | CORNELL UNIVERSITY (US) | 2018-01-04 | — | — | WO | disclosed |
| US-9841426-B2 | Intracellular organelle peptide targeted enzyme substrates | MARKER GENE TECHNOLOGIES, INC (US) | 2017-12-12 | — | — | US | disclosed |
| US-9677115-B2 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. (US) | 2017-06-13 | — | — | US | disclosed |
| US-20150219654-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | MARKER GENE TECHNOLOGIES, INC. | 2015-08-06 | — | — | US | disclosed |
| US-20130252268-A1 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. (US) | 2013-09-26 | — | — | US | disclosed |
| US-8460862-B2 | Enzyme substrates for visualizing acidic organelles | Marker Gene Technologies (US) | 2013-06-11 | — | — | US | disclosed |
| WO-2000017643-A2 | A SYSTEM FOR CELL-BASED SCREENING | CELLOMICS, INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| EP-0983498-A1 | A SYSTEM FOR CELL-BASED SCREENING | Cellomics, Inc. (US) | 2000-03-08 | — | — | EP | disclosed |
| WO-2000003246-A2 | A SYSTEM FOR CELL-BASED SCREENING | CELLOMICS, INC. (US) | 2000-01-20 | — | — | WO | disclosed |
| WO-1999063108-A1 | NOVEL PEROXIDASE SUBSTRATES AND THEIR USE IN CATALYZED REPORTER DEPOSITION | NEN LIFE SCIENCE PRODUCTS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| EP-0938675-A1 | ANALYSIS OF CARBOHYDRATES | AMERSHAM INTERNATIONAL plc (GB) | 1999-09-01 | — | — | EP | disclosed |
| US-5869689-A | DIAZAINDACENE METHINE DYES | MOLECULAR PROBES, INC (US) | 1999-02-09 | — | — | US | disclosed |
| US-5863748-A | p-Hydroxycinnamoyl-containing substrates for an analyte dependent enzyme activation system | NEW LIFE SCIENCE PRODUCTS, INC. (US) | 1999-01-26 | — | — | US | disclosed |
| WO-1998038490-A9 | A SYSTEM FOR CELL-BASED SCREENING | — | 1999-01-21 | — | — | WO | disclosed |
| WO-1998038490-A1 | A SYSTEM FOR CELL-BASED SCREENING | CELLOMICS, INC. (US) | 1998-09-03 | — | — | WO | disclosed |
| WO-1998015829-A1 | ANALYSIS OF CARBOHYDRATES | AMERSHAM INTERNATIONAL PLC (GB) | 1998-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10401361-B2 | Intracellular organelle peptide targeted enzyme substrates | GLG1, GBA3, MIA3 | KAT2B 3878/4885POLB 1486/4885MAPT 2204/4885 |
| US-20180120317-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | GLG1, GBA3, MIA3 | KAT2B 3878/4885POLB 1486/4885MAPT 2204/4885 |
| US-20150219654-A1 | INTRACELLULAR ORGANELLE PEPTIDE TARGETED ENZYME SUBSTRATES | GLG1, GBA3, MIA3 | KAT2B 3878/4885POLB 1486/4885MAPT 2204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.