Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | MDM4 | O15151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30404089 | 1.00 | KMT2A (0.57) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL19426629 | 1.00 | KMT2A (0.57) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL30402460 | 1.00 | KMT2A (0.57) | KMT2ACASP3MDM4TP53EPHX2 | |
| Hydrochloric Acid SCHEMBL30396303 | 0.99 | KMT2A (0.56) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL17282987 | 0.90 | KMT2A (0.55) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL15199950 | 0.90 | KMT2A (0.55) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL26478312 | 0.90 | KMT2A (0.55) | KMT2ACASP3MDM4TP53EPHX2 | |
| Hydrochloric Acid SCHEMBL30001047 | 0.89 | KMT2A (0.54) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL21474105 | 0.89 | KMT2A (0.56) | KMT2ACASP3MDM4TP53EPHX2 | |
| SCHEMBL21504338 | 0.89 | KMT2A (0.56) | KMT2ACASP3MDM4TP53EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916784-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-04-04 | — | — | CN | disclosed |
| WO-2010028190-A2 | COMPOUNDS, COMPOSITIONS AND METHODS OF USING SAME FOR MODULATING URIC ACID LEVELS | ARDEA BIOSCIENCES, INC. (US) | 2010-03-11 | — | — | WO | disclosed |