⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17696607 | 0.81 | — | — | |
| SCHEMBL9935099 | 0.74 | — | — | |
| SCHEMBL28048381 | 0.71 | — | — | |
| SCHEMBL20017367 | 0.71 | — | — | |
| SCHEMBL16691034 | 0.70 | — | — | |
| SCHEMBL14401832 | 0.70 | — | — | |
| SCHEMBL15366256 | 0.70 | — | — | |
| SCHEMBL13496740 | 0.70 | — | — | |
| SCHEMBL26913665 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL11201539 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12275720-B2 | Small molecule inhibitors of galectin-3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-04-15 | — | — | US | disclosed |
| US-20230192672-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB (US) | 2023-06-22 | — | — | US | disclosed |
| US-20230192672-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL MYERS SQUIBB (US) | 2023-06-22 | — | — | US | disclosed |
| EP-4146646-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | Bristol-Myers Squibb Company (US) | 2023-03-15 | — | — | EP | disclosed |
| CN-115551855-A | Small molecule inhibitors of galectin-3 | 百时美施贵宝公司 | 2022-12-30 | — | — | CN | disclosed |
| WO-2021226002-A1 | SMALL MOLECULE INHIBITORS OF GALECTIN-3 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-11-11 | — | — | WO | disclosed |
| EP-2900665-B1 | TRIAZOLYL DERIVATIVES AS SYK INHIBITORS | MERCK SHARP & DOHME (US) | 2018-01-03 | — | — | EP | disclosed |
| US-9586931-B2 | Triazolyl derivatives as Syk inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-03-07 | — | — | US | disclosed |
| US-20150239866-A1 | TRIAZOLYL DERIVATIVES AS SYK INHIBITORS | MERCK CANADA INC. (CA) | 2015-08-27 | — | — | US | disclosed |
| EP-2900665-A1 | TRIAZOLYL DERIVATIVES AS SYK INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2015-08-05 | — | — | EP | disclosed |
| CN-101014598-B | Aminocyclohexanes as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes | MERCK SHARP & DOHME | 2012-06-13 | — | — | CN | disclosed |
| US-20100069570-A1 | Functionalization of Polymers | ATRP Solutions, Inc. | 2010-03-18 | — | — | US | disclosed |
| US-20100069570-A1 | Functionalization of Polymers | ATRP Solutions, Inc. | 2010-03-18 | — | — | US | disclosed |
| CN-101014598-A | Aminocyclohexanes as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes | MERCK & CO INC (US) | 2007-08-08 | — | — | CN | disclosed |