Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.54 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.54 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | C1S | P09871 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4326927 | 0.88 | PARP1 (0.59) | PARP1PRSS1PARP10TNKSPARP15 | |
| SCHEMBL19732841 | 0.88 | PARP1 (0.59) | PARP1PRSS1PARP10TNKSPARP15 | |
| SCHEMBL30938280 | 0.88 | PARP1 (0.59) | PARP1PRSS1PARP10TNKSPARP15 | |
| SCHEMBL29686682 | 0.87 | PRSS1 (0.58) | PARP1PRSS1PARP10TNKSPARP15 | |
| SCHEMBL9448432 | 0.87 | PRSS1 (0.58) | PARP1PRSS1PARP10TNKSPARP15 | |
| SCHEMBL15987223 | 0.86 | PARP1 (0.61) | PARP1PRSS1PARP10TNKSPARP15 | |
| SCHEMBL203780 | 0.85 | PRSS1 (0.61) | PARP1PRSS1PARP10TNKSPARP15 | |
| SCHEMBL31133401 | 0.85 | KMT2A (0.71) | KMT2A | |
| SCHEMBL19983022 | 0.85 | KMT2A (0.71) | KMT2A | |
| SCHEMBL28029093 | 0.84 | PARP1 (0.62) | PARP1PRSS1PARP10TNKSPARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010028776-A1 | PIPERAZINE DERIVATIVES FOR BINDING AND IMAGING AMYLOID PLAQUES AND THEIR USE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-03-18 | — | — | WO | disclosed |
| EP-2163541-A1 | Piperazine derivatives for binding and imaging amyloid plaques and their use | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-03-17 | — | — | EP | disclosed |