Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | TOP2A | P11388 | 5/20 | 0.65 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.65 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.60 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 10/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6216504 | 0.90 | MEN1 (0.58) | MEN1KMT2ATOP2ATOP2BCACNA1F | |
| SCHEMBL1345769 | 0.89 | GSK3B (0.70) | MEN1KMT2ATOP2ATOP2BCACNA1F | |
| SCHEMBL5868648 | 0.89 | GSK3B (0.60) | MEN1KMT2ATOP2ATOP2BCACNA1F | |
| SCHEMBL8097562 | 0.89 | MEN1 (0.57) | MEN1KMT2ATOP2ATOP2BCACNA1F | |
| SCHEMBL12674061 | 0.89 | TOP2A (0.67) | MEN1KMT2ATOP2ATOP2BCACNA1F | |
| SCHEMBL9088265 | 0.88 | MEN1 (0.56) | MEN1KMT2ATOP2ATOP2BCACNA1F | |
| SCHEMBL9377798 | 0.86 | MEN1 (0.56) | MEN1KMT2ATOP2ATOP2BCACNA1F | |
| SCHEMBL8327189 | 0.86 | MEN1 (0.54) | MEN1KMT2ATOP2ATOP2BCACNA1F | |
| SCHEMBL12665523 | 0.86 | MEN1 (0.62) | MEN1KMT2ATOP2ATOP2BCACNA1F | |
| SCHEMBL9378534 | 0.86 | MEN1 (0.59) | MEN1KMT2ATOP2ATOP2BCACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62000469-A | — | — | None | — | — | JP | disclosed |
| JP-1019069-A | — | — | None | — | — | JP | disclosed |
| JP-63045261-A | — | — | None | — | — | JP | disclosed |
| EP-2013182-B1 | AMINOQUINOLONES AS GSK-3 INHIBITORS | KYORIN SEIYAKU KK (JP) | 2013-09-04 | — | — | EP | disclosed |
| EP-2383271-B1 | Aminoquinolones as GSK-3 Inhibitors | KYORIN SEIYAKU KK (JP) | 2013-07-10 | — | — | EP | disclosed |
| US-8063221-B2 | Aminoquinolones as GSK-3 inhibitors | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2011-11-22 | — | — | US | disclosed |
| US-8063221-B2 | Aminoquinolones as GSK-3 inhibitors | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2011-11-22 | — | — | US | disclosed |
| US-8063221-B2 | Aminoquinolones as GSK-3 inhibitors | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2011-11-22 | — | — | US | disclosed |
| EP-2383271-A1 | Aminoquinolones as GSK-3 Inhibitors | Kyorin Pharmaceutical Co., Ltd. (JP) | 2011-11-02 | — | — | EP | disclosed |
| EP-2383271-A1 | Aminoquinolones as GSK-3 Inhibitors | Kyorin Pharmaceutical Co., Ltd. (JP) | 2011-11-02 | — | — | EP | disclosed |
| JP-S6345261-A | NOVEL QUINOLONE DERIVATIVE, ESTER AND SALT THEREOF | DAINIPPON PHARMACEUT CO LTD | 1988-02-26 | — | — | JP | disclosed |
| EP-0247464-A1 | New quinolone compounds and a process for the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-12-02 | — | — | EP | disclosed |
| CN-87103138-A | New quinoline and preparation method thereof | — | 1987-11-04 | — | — | CN | disclosed |
| EP-0242789-A2 | Novel quinoline derivates and processes for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-10-28 | — | — | EP | disclosed |
| EP-0230053-A2 | 7-(Substituted)piperazinyl-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |
| EP-0221463-A2 | Quinoline derivatives and processes for preparation thereof | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-05-13 | — | — | EP | disclosed |
| CN-86107491-A | New quinoline and preparation method thereof | — | 1987-04-29 | — | — | CN | disclosed |
| US-4657913-A | Trifluoro- quinoline -3- carboxylic acids and their use as anti-bacterial agents | WARNER-LAMBERT COMPANY (US) | 1987-04-14 | — | — | US | disclosed |
| JP-S62469-A | NOVEL QUINOLONE DERIVATIVE AND ESTER AND SALT THEREOF | DAINIPPON PHARMACEUT CO LTD | 1987-01-06 | — | — | JP | disclosed |
| EP-0202763-A1 | 5,6-Difluoronaphthyridines and 5,6,8-trifluoro-quinolines as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-11-26 | — | — | EP | disclosed |