Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 9/20 | 0.65 |
| ▸ | SCN1A | P35498 | 2/20 | 0.61 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.61 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.61 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.61 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.61 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3159571 | 0.94 | SCN3A (0.75) | SCN3ASCN1ASCN5ASCN9ASCN2A | |
| SCHEMBL3163178 | 0.88 | SCN3A (0.66) | SCN3ASCN1ASCN5ASCN9ASCN2A | |
| SCHEMBL13448133 | 0.88 | SCN3A (0.83) | SCN3ASCN1ASCN5ASCN9ASCN2A | |
| SCHEMBL3165836 | 0.86 | SCN3A (0.62) | SCN3ASCN1ASCN5ASCN9ASCN2A | |
| SCHEMBL3161293 | 0.86 | SCN3A (0.75) | SCN3ASCN1ASCN5ASCN9ASCN2A | |
| SCHEMBL3171480 | 0.85 | SCN3A (0.71) | SCN3ASCN1ASCN5ASCN9ASCN2A | |
| SCHEMBL3159993 | 0.85 | SCN3A (0.68) | SCN3ASCN1ASCN5ASCN9ASCN2A | |
| SCHEMBL3166193 | 0.83 | SCN3A (0.76) | SCN3ASCN1ASCN5ASCN9ASCN2A | |
| SCHEMBL3160783 | 0.83 | SCN3A (0.68) | SCN3ASCN1ASCN5ASCN9ASCN2A | |
| SCHEMBL3162733 | 0.83 | SCN3A (0.68) | SCN3ASCN1ASCN5ASCN9ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010033824-A1 | SULFONAMIDE DERIVATIVES AS INHIBITORS OF ION CHANNELS | ICAGEN, INC. (US) | 2010-03-25 | — | — | WO | disclosed |