Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13448175 | 0.88 | APP (0.53) | SLC2A1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL13448161 | 0.88 | APP (0.53) | SLC2A1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL30280404 | 0.87 | SLC2A1 (0.56) | SLC2A1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL584781 | 0.87 | SLC2A1 (0.56) | SLC2A1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL13448124 | 0.87 | SLC2A1 (0.47) | SLC2A1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL13448420 | 0.83 | SLC2A1 (0.42) | SLC2A1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL13448207 | 0.83 | SLC2A1 (0.52) | SLC2A1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL13448412 | 0.83 | APP (0.47) | SLC2A1NPC1RAB9APOLBSMN1; SMN2 | |
| SCHEMBL13413505 | 0.82 | NPC1 (0.57) | NPC1RAB9APOLBSMN1; SMN2HPGD | |
| SCHEMBL13448126 | 0.82 | SLC2A1 (0.43) | SLC2A1NPC1RAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671033-B2 | Amphiphilic dendritic dipeptides and their self-assembly into helical pores | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-03-02 | — | — | US | disclosed |