Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.61 |
| ▸ | DRD3 | P35462 | 20/20 | 0.61 |
| ▸ | DRD2 | P14416 | 5/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1967971 | 0.92 | HTR2A (0.60) | HTR2ADRD3DRD2 | |
| SCHEMBL3453145 | 0.92 | HTR2A (0.60) | HTR2ADRD3DRD2 | |
| SCHEMBL3453757 | 0.90 | HTR2A (0.56) | HTR2ADRD3DRD2 | |
| SCHEMBL1971346 | 0.90 | HTR2A (0.56) | HTR2ADRD3DRD2 | |
| SCHEMBL3453755 | 0.90 | HTR2A (0.56) | HTR2ADRD3DRD2 | |
| SCHEMBL3453875 | 0.90 | HTR2A (0.65) | HTR2ADRD3DRD2 | |
| SCHEMBL1971312 | 0.90 | HTR2A (0.65) | HTR2ADRD3DRD2 | |
| SCHEMBL1968037 | 0.90 | HTR2A (0.60) | HTR2ADRD3DRD2 | |
| SCHEMBL3453578 | 0.90 | HTR2A (0.60) | HTR2ADRD3DRD2 | |
| SCHEMBL3453149 | 0.89 | HTR2A (0.64) | HTR2ADRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010031735-A1 | PIPERAZINE D3 AND 5-HT2A RECEPTOR MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-25 | — | — | WO | disclosed |