Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.37 |
| ▸ | JAK1 | P23458 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21665970 | 0.89 | JAK2 (0.37) | JAK2JAK1ACACBEPHX2KDM1A | |
| SCHEMBL31756360 | 0.83 | JAK2 (0.37) | JAK2JAK1ACACBEPHX2ALDH1A1 | |
| SCHEMBL26544362 | 0.82 | EPHX2 (0.38) | JAK2JAK1ACACBEPHX2KDM1A | |
| SCHEMBL19389951 | 0.82 | EPHX2 (0.38) | JAK2JAK1ACACBEPHX2KDM1A | |
| SCHEMBL23578904 | 0.81 | EPHX2 (0.37) | JAK2JAK1ACACBEPHX2KDM1A | |
| SCHEMBL30532870 | 0.81 | EPHX2 (0.37) | JAK2JAK1ACACBEPHX2KDM1A | |
| SCHEMBL31756246 | 0.81 | EPHX2 (0.37) | JAK2JAK1ACACBEPHX2KDM1A | |
| SCHEMBL25151395 | 0.79 | JAK2 (0.38) | JAK2JAK1ACACBEPHX2KDM1A | |
| SCHEMBL27829228 | 0.79 | JAK2 (0.42) | JAK2JAK1ACACBEPHX2ALDH1A1 | |
| SCHEMBL28558549 | 0.78 | JAK2 (0.38) | JAK2JAK1ACACBEPHX2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836211-B1 | MACROLIDES | PFIZER PROD INC (US) | 2010-03-03 | — | — | EP | disclosed |