Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.39 |
| ▸ | CDC25B | P30305 | 6/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.37 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | GJB2 | P29033 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13449558 | 1.00 | NT5E (0.41) | NT5EBCHEACHETACR2HTR1A | |
| SCHEMBL13449546 | 0.87 | TSHR (0.38) | NT5E | |
| SCHEMBL11673910 | 0.86 | NT5E (0.43) | NT5EBCHEACHETACR2HTR1A | |
| SCHEMBL11673905 | 0.86 | NT5E (0.43) | NT5EBCHEACHETACR2HTR1A | |
| SCHEMBL14599853 | 0.85 | NT5E (0.44) | NT5EBCHEACHETACR2HTR1A | |
| SCHEMBL20952828 | 0.85 | NT5E (0.44) | NT5EBCHEACHETACR2HTR1A | |
| SCHEMBL13572465 | 0.85 | NT5E (0.44) | NT5EBCHEACHETACR2HTR1A | |
| SCHEMBL16027750 | 0.85 | NT5E (0.44) | NT5EBCHEACHETACR2HTR1A | |
| SCHEMBL11673525 | 0.85 | NT5E (0.44) | NT5EBCHEACHETACR2HTR1A | |
| SCHEMBL16689643 | 0.82 | NT5E (0.38) | NT5EBCHEACHETACR2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120263649-A1 | DETECTION OF MYCOBACTERIA | ISIS INNOVATION LIMITED (GB) | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120263649-A1 | DETECTION OF MYCOBACTERIA | LY96, MICA, CD74 | NT5E 2821/4885BCHE 2774/4885ACHE 772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.