Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELP | P16109 | 3/20 | 0.41 |
| ▸ | TNF | P01375 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | FGF1 | P05230 | 2/20 | 0.37 |
| ▸ | FGF2 | P09038 | 2/20 | 0.37 |
| ▸ | VEGFA | P15692 | 2/20 | 0.37 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13449599 | 0.95 | PTPN1 (0.46) | SELPPTPN1PTPN2PTPN11SSTR1 | |
| SCHEMBL3756791 | 0.82 | SSTR1 (0.46) | SELPTNFPTPN1PTPN2PTPN11 | |
| SCHEMBL38652098 | 0.79 | PTPN1 (0.49) | TNFPTPN1PTPN2PTPN11SSTR1 | |
| SCHEMBL12837368 | 0.78 | TLR4 (0.42) | TNFFGF1FGF2VEGFAHPSE | |
| SCHEMBL26455294 | 0.76 | SSTR1 (0.43) | TNFPTPN1PTPN2PTPN11SSTR1 | |
| SCHEMBL13449592 | 0.76 | SSTR1 (0.48) | PTPN1PTPN2PTPN11SSTR1SSTR2 | |
| SCHEMBL11584750 | 0.76 | NT5E (0.55) | SELPPTPN1PTPN2PTPN11SSTR1 | |
| SCHEMBL7933032 | 0.76 | NT5E (0.55) | SELPPTPN1PTPN2PTPN11SSTR1 | |
| SCHEMBL17867736 | 0.76 | TNF (0.44) | TNFPTPN1SSTR1SSTR2SSTR4 | |
| SCHEMBL11581477 | 0.76 | NT5E (0.55) | SELPPTPN1PTPN2PTPN11SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120263649-A1 | DETECTION OF MYCOBACTERIA | ISIS INNOVATION LIMITED (GB) | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120263649-A1 | DETECTION OF MYCOBACTERIA | LY96, MICA, CD74 | SELP 4354/4885TNF 3603/4885PTPN1 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.