⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17706382 | 0.71 | — | — | |
| SCHEMBL869777 | 0.71 | — | — | |
| SCHEMBL13981306 | 0.71 | — | — | |
| SCHEMBL13647106 | 0.71 | — | — | |
| SCHEMBL19451208 | 0.71 | — | — | |
| SCHEMBL10188398 | 0.69 | — | — | |
| SCHEMBL15030472 | 0.67 | — | — | |
| SCHEMBL19993541 | 0.67 | — | — | |
| SCHEMBL28553425 | 0.65 | — | — | |
| SCHEMBL25798579 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212165-A1 | FLUOROPYRROLOPYRIDINE COMPOUND AND APPLICATION THEREOF | WUXI LIFE FOUNTAIN BIOTECH CO., LTD (CN) | 2023-07-06 | — | — | US | disclosed |
| WO-2019238067-A1 | PYRROLO [2, 3-B] PYRIDINES OR PYRROLO [2, 3-B] PYRAZINES AS HPK1 INHIBITOR AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2019-12-19 | — | — | WO | disclosed |
| EP-1704165-B1 | GLP-1 COMPOUNDS | NOVO NORDISK AS (DK) | 2010-03-17 | — | — | EP | disclosed |