Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 9/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174134 | 0.87 | CYSLTR1 (0.51) | CYSLTR1GRM2CYSLTR2TDP1MEN1 | |
| SCHEMBL13452638 | 0.84 | CYSLTR1 (0.47) | CYSLTR1GRM2CYSLTR2TDP1MEN1 | |
| SCHEMBL3174233 | 0.83 | CYSLTR1 (0.53) | CYSLTR1GRM2CYSLTR2TDP1MEN1 | |
| SCHEMBL3167100 | 0.82 | CYSLTR1 (0.53) | CYSLTR1GRM2CYSLTR2TDP1MEN1 | |
| SCHEMBL13452640 | 0.82 | CYSLTR1 (0.55) | CYSLTR1GRM2CYSLTR2TDP1MEN1 | |
| SCHEMBL2893372 | 0.81 | CYSLTR1 (0.60) | CYSLTR1GRM2CYSLTR2TDP1LMNA | |
| SCHEMBL3177503 | 0.80 | CYSLTR1 (0.59) | CYSLTR1GRM2CYSLTR2LMNAMAPT | |
| SCHEMBL13452563 | 0.80 | CYSLTR1 (0.65) | CYSLTR1GRM2CYSLTR2TDP1LMNA | |
| SCHEMBL3163740 | 0.79 | CYSLTR1 (0.71) | CYSLTR1GRM2CYSLTR2TDP1MEN1 | |
| SCHEMBL3173403 | 0.78 | CYSLTR1 (0.46) | CYSLTR1GRM2CYSLTR2TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817300-B1 | POTENTIATORS OF GLUTAMATE RECEPTORS | LILLY CO ELI (US) | 2010-03-17 | — | — | EP | disclosed |