Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 13/20 | 0.68 |
| ▸ | CYSLTR1 | Q9Y271 | 13/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3168336 | 0.90 | GRM2 (0.72) | GRM2CYSLTR1MAPTL3MBTL1HTT | |
| SCHEMBL3178712 | 0.88 | GRM2 (0.70) | GRM2CYSLTR1MAPTL3MBTL1HTT | |
| SCHEMBL3173172 | 0.83 | GRM2 (0.68) | GRM2CYSLTR1MAPTL3MBTL1HTT | |
| SCHEMBL13452806 | 0.81 | GRM2 (0.71) | GRM2CYSLTR1MAPTL3MBTL1HTT | |
| SCHEMBL3171343 | 0.81 | GRM2 (1.00) | GRM2CYSLTR1 | |
| SCHEMBL3173109 | 0.77 | GRM2 (0.68) | GRM2CYSLTR1MAPTL3MBTL1HTT | |
| SCHEMBL13452877 | 0.76 | GRM2 (0.69) | GRM2CYSLTR1MAPTL3MBTL1HTT | |
| Hydrochloric Acid SCHEMBL27831476 | 0.75 | MRGPRX4 (0.56) | GRM2CYSLTR1MAPTL3MBTL1HTT | |
| SCHEMBL3164262 | 0.75 | CYSLTR1 (1.00) | GRM2CYSLTR1 | |
| SCHEMBL13452631 | 0.75 | MAPT (0.56) | GRM2CYSLTR1MAPTL3MBTL1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817300-B1 | POTENTIATORS OF GLUTAMATE RECEPTORS | LILLY CO ELI (US) | 2010-03-17 | — | — | EP | disclosed |